Top 5 Best Ergonomic Mice with Replaceable Batteries
With so many choices out there, picking the right takes time.
We looked at reviews, specs, and overall performance to narrow it down.
The best option wasn’t the most expensive — but it delivered where it counts.
1
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
9.4
Amazon.com
2
ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for...
8.8
Amazon.com
3
memzuoix 2.4G Wireless Mouse, 1400 DPI Computer Mouse with USB Receiver, Portable Wireless USB Mice Battery Powered Cordless Mice for Laptop, PC, Desktop, 5...
8.6
Amazon.com
4
TECKNET Ergonomic Mouse, Rechargeable Wireless Bluetooth Mouse (BT 5.0/5.0+2.4G), Vertical Mouse with Volume Knob, Quiet Clicks, Cordless Mice 6 Adjustable...
8.6
Amazon.com
5
TECKNET Ergonomic Mouse, 4800 DPI Wireless Vertical Mouse, 5 Adjustable DPI Levels, 6 Buttons, 2.4G Silent Wireless Mouse for Laptop, PC, Chromebook, Mac -...
7.8
Amazon.com
Top Pick
This is the product that stood out most — for performance, price, and overall value.
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
$19.99
PRIMEPRIME
in stock
Amazon.com
Features
| Warranty | 18 Months |
| Color | Black |
- 【Ergonomic Design】Ergonomic mouse with Ergonomic Design, 52°angle to the tabletop. A natural handshake position effectively relieves pressure on the wrist and arm, preventing RSI syndrome caused by long-term mouse use. It is the ideal choice for prolonged office work
- 【4800 High DPI】5 adjustable DPI settings: 4800/3200/2400/1600/800, catering to different usage habits. Even if you're new to it, you can easily master the mouse. TECKNET ergonomic wireless mouse optical tracking provides the smoothest and most precise cursor control on most surfaces
- 【Comfortable Shape for Small/Medium Hands】The shape is rounded and comfortable with no sharp corners. Unlike other mice, this mouse is more suitable for small/medium hands, bringing a comfortable using experience and slowing down wrist fatigue. Product size: 4.13in*2.55in
- 【Quick Click Buttons】The vertical mouse wireless added forward/back buttons provide convenience for web browsing. (Side buttons not supported on MAC OS).The features a silent click design, reducing click noise by over 99%, while ensuring optimal performance. This means you can feel every click but hardly hear any sound (note: forward/back buttons are not silent)
- 【Stable Wireless Connection】The ergonomic mouse wireless uses 2.4GHz wireless technology, providing a stable and accurate connection without the need for any drivers. Simply plug the USB receiver into your laptop to start using the mouse, with a connection range of up to 32ft
- 【Wide Compatibility】The mouse ergonomic is compatible with a wide range of devices and can be used on desktops, laptops, PCs, MacBooks and other devices. Works with Windows 11/10/8/7/XP and Mac OS X10.4. It has a silent feature that allows it to be used in libraries, homes, offices, and other situations where low sound levels are required
Top Picks Compared
Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
$19.99
PRIMEPRIME
in stock
Amazon.com
Features
| Warranty | 18 Months |
| Color | Black |
- 【Ergonomic Design】Ergonomic mouse with Ergonomic Design, 52°angle to the tabletop. A natural handshake position effectively relieves pressure on the wrist and arm, preventing RSI syndrome caused by long-term mouse use. It is the ideal choice for prolonged office work
- 【4800 High DPI】5 adjustable DPI settings: 4800/3200/2400/1600/800, catering to different usage habits. Even if you're new to it, you can easily master the mouse. TECKNET ergonomic wireless mouse optical tracking provides the smoothest and most precise cursor control on most surfaces
- 【Comfortable Shape for Small/Medium Hands】The shape is rounded and comfortable with no sharp corners. Unlike other mice, this mouse is more suitable for small/medium hands, bringing a comfortable using experience and slowing down wrist fatigue. Product size: 4.13in*2.55in
- 【Quick Click Buttons】The vertical mouse wireless added forward/back buttons provide convenience for web browsing. (Side buttons not supported on MAC OS).The features a silent click design, reducing click noise by over 99%, while ensuring optimal performance. This means you can feel every click but hardly hear any sound (note: forward/back buttons are not silent)
- 【Stable Wireless Connection】The ergonomic mouse wireless uses 2.4GHz wireless technology, providing a stable and accurate connection without the need for any drivers. Simply plug the USB receiver into your laptop to start using the mouse, with a connection range of up to 32ft
- 【Wide Compatibility】The mouse ergonomic is compatible with a wide range of devices and can be used on desktops, laptops, PCs, MacBooks and other devices. Works with Windows 11/10/8/7/XP and Mac OS X10.4. It has a silent feature that allows it to be used in libraries, homes, offices, and other situations where low sound levels are required
ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for...
$26.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | Protoarc B0CX18LHWS |
| Model | EM11 NL |
| Warranty | 2 YEAR |
| Color | Black |
| Size | One Size |
- Connect up to 3 Devices: This ergonomic wireless mouse features dual BT 5.0 and 2.4G USB connectivity modes for simultaneous connection of up to 3 different devices, and is compatible with Windows 8, Windows 10 or higher, Mac OS X 10.12 or higher, and Android 4.3 or higher
- Rechargeable Ergonomic Mouse: The Bluetooth Vertical Mouse has a built-in 500mAh Li-Ion battery that can be conveniently recharged using the included Type-C cable
- Ergonomic Vertical Design: The ergonomic mouse wireless keeps your wrist naturally straight, putting your forearm and wrist in a more natural and relaxed position, which can reduce discomfort and strain, helping to improve productivity and reduce the risk of repetitive strain injuries compared to a standard mouse. Warm tips: We encourage you to relax your palm and hold the mouse naturally when using a vertical mouse
- Learning curve: Since it takes a learning curve to get used to the shape when using our ergonomic mouse for the first time, it may cause inconvenience to your mouse grip, We recommend that you take 1-2 weeks to get used to it, as many users find that it will help reduce the pressure and pain on your wrist caused by long-term use of the mouse and improve comfort
- Notes: We recommend that small to medium hands use our ergonomic vertical mouse. Please measure the size before ordering for a better fit and more comfort
- Adjustable Dpi & High Performance: 1000/1600/2400 DPI levels provide higher sensitivity than standard optical mice for precise optical tracking; with the back and forward buttons, you can easily navigate websites and increase work efficiency. Note: All buttons are not programmable and the forward and back buttons are not compatible with Mac OS systems
- Quiet Clicking: The silent click sound of the left and right mouse buttons help you focus on your work, Note:the middle scroll wheel and and the back/forward buttons are not silent.
TECKNET Ergonomic Mouse, Rechargeable Wireless Bluetooth Mouse (BT 5.0/5.0+2.4G), Vertical Mouse with Volume Knob, Quiet Clicks, Cordless Mice 6 Adjustable...
$24.99
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | TK-MS042 |
| Model | TK-MS042 |
| Warranty | 3 years |
| Color | Black |
- One-Click Multi-Device Control: This Bluetooth mouse enables seamless switching across 3 devices with advanced 2.4G + Dual Bluetooth 5.0 connectivity. Easily toggle between your computer (via USB-A receiver), smartphone, and tablet with just one click—no need for repeated pairing. Perfect for multitaskers who work, browse, and stream without interruption.
- Media Control at Your Fingertips: Featuring a dedicated media control knob, you can instantly adjust volume and play/pause directly—all without lifting your fingers off the TECKNET optical wireless mouse. Enjoy seamless control that keeps you in the flow, whether you're working or relaxing.
- Ergonomic Comfort: Say goodbye to wrist strain and hello to pain-free productivity! This ergonomic vertical mouse features a 57° tilt design and integrated palm support, this ergonomic mouse keeps your hand in a natural, relaxed position, helping prevent wrist fatigue and carpal tunnel syndrome—perfect for long hours of work.
- Fast Charging & Long Battery Life: Enjoy up to 60 days of use on just 2.5 hours of charging with our long-lasting rechargeable wireless mouse. The 500mAh battery and Type-C fast charging (cable included) eliminate the hassle of battery swaps or interruptions.
- Silent Click: Engineered with ultra-quiet button mechanisms, this silent USB computer mouse offers soft, tactile clicks without distracting noise. Perfect for libraries, late-night work, important meetings, and shared spaces—stay focused and productive without disturbing others in any environment.
- 36-Month Warranty: If you experience any issues while using the product, our dedicated customer service team is here to assist you promptly and professionally. Enjoy peace of mind with the TECKNET 36-Month Warranty (Registered Customer Only).
memzuoix 2.4G Wireless Mouse, 1400 DPI Computer Mouse with USB Receiver, Portable Wireless USB Mice Battery Powered Cordless Mice for Laptop, PC, Desktop, 5...
$11.99
$19.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | GAYI |
| Model | MidMouse Black |
| Color | Black |
- 【MAXIMUM HAND-FEELING】 Modern contoured shape, sweat-resistant and skin-friendly finish are for maximum comfort and support. The thoughtful ring and little finger rest provide extra comfort. The sturdy scroll wheel with rubber makes sure that your hand will not slip when scrolling.
- 【PLUG & PLAY SUPER EASY TO USE】Really plug & play design, no drivers need to be installed. 2.4GHz wireless transmission technology provides a powerful and reliable connection up to 43.0ft. Portable design make it easy to store in bag. It's the best mouse for a gifts.
- 【STRONG DURABILITY & LONG WORKING DISTANCE】Passed 6,000,000 times keystroke test to guarantee extra durability. 2.4GHz wireless technology and professional chip ensure longer working distance.
- 【EXTREMELY LOW POWER CONSUMPTION】 It takes 2 AAA Batteries(NOT Included) to operate this wireless mouse, and it will turn to sleep mode in 10mins of inactivity for energy saving, can be easily activated by clicking any buttons.
- 【WIDE COMPATIBILITY】Well compatible with Windows 7/8/10/XP, Vista 7/8, Mac and Linux etc. The cordless computer mouse for Laptop, Desktop, PC, Macbook, and other devices. This wireless mouse enjoys 45 days money-back and a 365-day worry-free warranty. Notice, the side buttons are not available for Mac OS, but the other function can be used normally.
TECKNET Ergonomic Mouse, 4800 DPI Wireless Vertical Mouse, 5 Adjustable DPI Levels, 6 Buttons, 2.4G Silent Wireless Mouse for Laptop, PC, Chromebook, Mac -...
$17.99
PRIMEPRIME
in stock
Amazon.com
Features
| Model | TK-MS017 |
| Warranty | 36 Months Warranty (Registered Only) |
| Color | Black |
- 【Ergonomic Design】Ergonomic mouse with Ergonomic Design, 52°angle to the tabletop. A natural handshake position effectively relieves pressure on the wrist and arm, preventing RSI syndrome caused by long-term mouse use. It is the ideal choice for prolonged office work
- 【4800 High DPI】5 adjustable DPI settings: 4800/3200/2400/1600/800, catering to different usage habits. Even if you're new to it, you can easily master the mouse. TECKNET ergonomic wireless mouse optical tracking provides the smoothest and most precise cursor control on most surfaces
- 【Comfortable Shape for Small/Medium Hands】The shape is rounded and comfortable with no sharp corners. Unlike other mice, this mouse is more suitable for small/medium hands, bringing a comfortable using experience and slowing down wrist fatigue. Product size: 4.13in*2.55in.
- 【Quick Click Buttons】The vertical mouse wireless added forward/back buttons provide convenience for web browsing. (Side buttons not supported on MAC OS).The features a silent click design, reducing click noise by over 99%, while ensuring optimal performance. This means you can feel every click but hardly hear any sound (note: forward/back buttons are not silent)
- 【Stable Wireless Connection】The ergonomic mouse wireless uses 2.4GHz wireless technology, providing a stable and accurate connection without the need for any drivers. Simply plug the USB receiver into your laptop to start using the mouse, with a connection range of up to 32ft
- 【Wide Compatibility】The mouse ergonomic is compatible with a wide range of devices and can be used on desktops, laptops, PCs, MacBooks and other devices. Works with Windows 11/10/8/7/XP and Mac OS X10.4. It has a silent feature that allows it to be used in libraries, homes, offices, and other situations where low sound levels are required.
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