The 5 Best Ergonomic Mice for Seniors

Not every is worth considering in 2025.

We looked at reviews, specs, and overall performance to narrow it down.

One came out ahead.

1
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
9.5
Amazon.com
2
TECKNET Ergonomic Mouse Wireless, Echargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB-A Vertical Mouse for Laptop,5 Adjustable 4800 DPI, Computer,MacBook, Desktop(Not-USB-C)
TECKNET Ergonomic Mouse Wireless, Echargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB-A Vertical Mouse for Laptop,5 Adjustable 4800...
9
Amazon.com
3
Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
9
Amazon.com
4
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
8.9
Amazon.com
5
TECKNET 2.4G Ergonomic Mouse Vertical Wireless - 4800 DPI Optical Carpal Tunnel Mouse Right Hand, 5 Adjustable DPI, Quiet Clicks, 6 Buttons for Laptop, Desktop, PC, Computer - Black
TECKNET 2.4G Ergonomic Mouse Vertical Wireless - 4800 DPI Optical Carpal Tunnel Mouse Right Hand, 5 Adjustable DPI, Quiet Clicks, 6 Buttons for Laptop,...
8.6
Amazon.com

Top Pick

This is the product that stood out most — for performance, price, and overall value.

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black

$29.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 25, 2025 11:45 pm

Features

Part Number AK-98ANWVM-UBA
Model AK-98ANWVM-UBA
Color Black
Is Adult Product
  • Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
  • 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
  • Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.

Top Picks Compared

Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black

$29.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 25, 2025 11:45 pm

Features

Part Number AK-98ANWVM-UBA
Model AK-98ANWVM-UBA
Color Black
Is Adult Product
  • Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
  • 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
  • Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.

Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100

$25.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 25, 2025 11:45 pm

Features

Part Number AK-98ANWVM-BA-0013
Model AK-98ANWVM-BA
Color Black
  • Ultimate Comfort: Embrace the comfort of Anker's Ergonomic Mouse, scientifically designed to encourage healthy neutral "handshake" wrist and arm positions. This wired mouse ensures smoother movement and significantly less strain, making it an ideal choice for extended computer use.
  • Enhanced Sensitivity: Experience precision like never before with our 1000/1600 DPI Resolution Optical Tracking Technology. This wired ergonomic mouse offers superior sensitivity compared to standard optical mice, ensuring smooth and precise tracking on a variety of surfaces to boost your productivity and computing experience.
  • Effortless Navigation: Navigate webpages with ease using the added next/previous buttons. This ergonomic wired mouse is not only ideal for internet surfers but also for gamers and professionals who spend long hours on the computer.
  • Compact and Lightweight: The Anker Vertical Ergonomic Optical Mouse, with its 1.5m/4.9ft USB cable and dimensions of 120*62.8*74.8 mm, offers a lightweight design of just 5.3 oz, ensuring a comfortable and convenient user experience.
  • Customer Value: Our package includes 1 Anker Vertical Ergonomic Optical Wired Mouse (with 4.9 ft cable), and a detailed instruction manual. We are committed to our customers and offer an 18-month warranty along with a lifetime technical support guarantee.

TECKNET Ergonomic Mouse Wireless, Echargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB-A Vertical Mouse for Laptop,5 Adjustable 4800...

$24.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 25, 2025 11:45 pm

Features

Model TK-MS007
Warranty 36 Months
Color Black
  • Ergonomic Design: This ergonomic mouse promotes a natural wrist and arm position, minimizing hand fatigue from prolonged use. With a vertical layout, the vertical mouse aids in maintaining a comfortable posture, reducing shoulder and neck strain.
  • Long-Lasting & Rapid Charging: Equipped with a 600mAh battery, the ergonomic mouse wireless fully charges in 1.5 hours via Type-C (cable included). The vertical mouse delivers a 2-month runtime per charge(depending on the actual frequency of use).
  • Stable Wireless Vertical Mouse: 2.4 GHz technology ensures reliable 10m connectivity with zero interference. Plug-and-play via nano USB-A receiver (Not Bluetooth). Ergonomic design maintains seamless productivity for office/remote professionals.
  • Silent Ergonomic Mouse Wireless: Silent-click tech eliminates noise in shared spaces (libraries/offices/homes). The vertical mouse is perfect for mobile workers in noise-sensitive environments, blending ergonomic comfort with wireless convenience. Note: The left and right click keys of this silent mouse are silent, and the other auxiliary keys are not silent.
  • Adjustable DPI Vertical Mouse: 5-step 4800-800 DPI adapts to tasks/habits. Tru-Wave optical tracking surpasses traditional mice with enhanced sensitivity, ensuring precision on multiple surfaces (excluding glass). Professional-grade responsiveness for graphic design/office workflows.
  • Wide Compatibility: 2.4GHz ergonomic mouse wireless ensures stable connectivity with USB-A devices (desktops/laptops/PCs). The vertical mouse seamlessly fits most computer models featuring USB-A port(Important Note: This 2.4 GHz wireless mouse supports UsB-A ports and cannot be connected directly to a UsB-C port.)
  • Power Saving Mode: The ergonomic mouse wireless Features an automatic sleep mode that automatically turns off and saves power after 8 minutes of inactivity—click any button to reactivate the vertical mouse.

TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black

$19.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 25, 2025 11:45 pm

Features

Warranty 18 Months
Color Black
  • 【Ergonomic Design】Ergonomic mouse with Ergonomic Design, 52°angle to the tabletop. A natural handshake position effectively relieves pressure on the wrist and arm, preventing RSI syndrome caused by long-term mouse use. It is the ideal choice for prolonged office work
  • 【4800 High DPI】5 adjustable DPI settings: 4800/3200/2400/1600/800, catering to different usage habits. Even if you're new to it, you can easily master the mouse. TECKNET ergonomic wireless mouse optical tracking provides the smoothest and most precise cursor control on most surfaces
  • 【Comfortable Shape for Small/Medium Hands】The shape is rounded and comfortable with no sharp corners. Unlike other mice, this mouse is more suitable for small/medium hands, bringing a comfortable using experience and slowing down wrist fatigue. Product size: 4.13in*2.55in
  • 【Quick Click Buttons】The vertical mouse wireless added forward/back buttons provide convenience for web browsing. (Side buttons not supported on MAC OS).The features a silent click design, reducing click noise by over 99%, while ensuring optimal performance. This means you can feel every click but hardly hear any sound (note: forward/back buttons are not silent)
  • 【Stable Wireless Connection】The ergonomic mouse wireless uses 2.4GHz wireless technology, providing a stable and accurate connection without the need for any drivers. Simply plug the USB receiver into your laptop to start using the mouse, with a connection range of up to 32ft
  • 【Wide Compatibility】The mouse ergonomic is compatible with a wide range of devices and can be used on desktops, laptops, PCs, MacBooks and other devices. Works with Windows 11/10/8/7/XP and Mac OS X10.4. It has a silent feature that allows it to be used in libraries, homes, offices, and other situations where low sound levels are required

TECKNET 2.4G Ergonomic Mouse Vertical Wireless - 4800 DPI Optical Carpal Tunnel Mouse Right Hand, 5 Adjustable DPI, Quiet Clicks, 6 Buttons for Laptop,...

$17.98 $29.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 25, 2025 11:45 pm

Features

Model TK-MS007
Warranty 36 Months
Color Black
  • ARM PROTECTION: The ergonomic vertical mouse allows you to adjust your arm and wrist for a comfortable position and less stress. An adaptation period of 3-7 days is recommended for optimal comfort.
  • PRECISE CONTROL: With 5 Adjustable DPI 4800/3200/2400/1600/800, providing higher sensitivity for smooth and precise tracking.
  • SILENT CLICKS: Clicking noise is reduced by more than 90%, avoiding disturbing others and ensuring your office or home work not be interrupted.
  • EASY TO USE: Just plug the 2.4G receiver for 49ft connection distance.The vertical mice requires an available USB-A port. An adapter may be needed for computers with only USB-C ports.
  • ENERGY SAVING: The computer mice will enter sleep mode after 8 minutes of inactivity, press the left or right button to wake it up. The erqonomic mice is required 2XAAA batteries(not included).
  • WIDE USE: The ergo mouse is compatible for various computer s such as laptop, desktop, pc, and Systerms such as Windows 11/10/8/7/XP/Vista/Linux.
  • 2 SIDE BUTTONS: The forward/backward buttons will greatly improve your work efficiency when browsing websites/emails. (Note: The side buttons are not suitable for Mac systems).
  • 36 MONTH SUPPORT: If you encounter any problems in using the product, feel free to reach out to the TECKNET friendly customer service, enjoying 36-Month Support(Registered Only).
  • Red Indicator Light: The LED light will flash red when you switch different DPI and when the battery is low.

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Digital Wellness Labs
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