Best Premium Ergonomic Keyboard and Mouse Combos

With so many choices out there, picking the right takes time.

We compared dozens of products to figure out which ones are worth your attention.

One stood out across the board.

1
ProtoArc Ergonomic Keyboard Mouse, EKM01 Plus Full Size Wireless Bluetooth Ergo Keyboard Mouse Combo, Cushioned Palm Rest, Split Design, Rechargeable, Compatible for Windows, Mac OS - Gray and Black
ProtoArc Ergonomic Keyboard Mouse, EKM01 Plus Full Size Wireless Bluetooth Ergo Keyboard Mouse Combo, Cushioned Palm Rest, Split Design, Rechargeable,...
9.6
Amazon.com
2
Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Keys Ergonomic Keyboard with Wrist Rest and 3-Level DPI Adjustable Wireless Ergonomic Mouse for Windows, Mac OS Desktop/Laptop/PC(Black)
Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Keys Ergonomic Keyboard with Wrist Rest and 3-Level DPI Adjustable Wireless Ergonomic Mouse for...
9
Amazon.com
3
ProtoArc Ergonomic Wireless Keyboard Mouse, EKM01 Plus Full Size Ergo Bluetooth Keyboard Mouse Combo, Split Design, Wrist Rest, Multi-Device, Rechargeable, for Windows/Mac OS - Black
ProtoArc Ergonomic Wireless Keyboard Mouse, EKM01 Plus Full Size Ergo Bluetooth Keyboard Mouse Combo, Split Design, Wrist Rest, Multi-Device, Rechargeable,...
8.4
Amazon.com
4
Logitech Wave Keys MK670 Combo, Wireless Ergonomic Keyboard with Signature M550 L Wireless Mouse, Comfortable Natural Typing, Bluetooth, Logi Bolt, for Multi-OS, Windows/Mac - Graphite
Logitech Wave Keys MK670 Combo, Wireless Ergonomic Keyboard with Signature M550 L Wireless Mouse, Comfortable Natural Typing, Bluetooth, Logi Bolt, for...
7.9
Amazon.com
5
Ergonomic Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Key Board with Cushioned Palm Rest, Natural Typing, 3 DPI Adjustable Mouse, USB-A & C for Computer/Laptop/Mac/Tablet – Sablute
Ergonomic Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Key Board with Cushioned Palm Rest, Natural Typing, 3 DPI Adjustable Mouse, USB-A & C for...
7.6
Amazon.com

Top Pick

This is the product that stood out most — for performance, price, and overall value.

ProtoArc Ergonomic Keyboard Mouse, EKM01 Plus Full Size Wireless Bluetooth Ergo Keyboard Mouse Combo, Cushioned Palm Rest, Split Design, Rechargeable,...

$99.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 28, 2025 1:45 am

Features

Warranty 1 Year
Color gray/black
  • Full-Size Ergonomic Comfort: Unlike standard keyboards, our wireless ergonomic keyboard is featured with full-size layout, curved and split keyframe design, helping to position your wrist and forearm in a more natural, relaxed typing posture. Premium ergonomic comfort that boosts productivity for all-day typing.
  • Cushioned Palm Rest: Curved wrist rest with soft memory foam layer offers typing comfort with more wrist support and less wrist bending. 4 Adjustable tilt legs position the keyboard at a perfect angle to keep your wrist relaxed and comfortable while sitting or standing.
  • Switch up to 3 Devices: Our wireless ergonomic keyboard and mouse can be connected up to 3 devices simultaneously through USB receiver or Bluetooth, seamlessly realize quick switch between 3 devices by just pressing a single button. Well compatible with Windows 7/8/10, Mac OS X 10.12, Android 4.3 or higher.
  • Precision Tracking: The contoured ergonomic mouse is designed with palm and thumb rest which provides better wrist support and keeps your hand in a natural position, effectively reduces the wrist tension and pain. 2000 DPI allows you to gain more precise control, forward/backward buttons provide more convenience for webpage browsing.
  • Type-C Charging: The ergonomic keyboard mouse combo are built-in 500mAh rechargeable lithium battery with 250 hours of standby time after 2 hours of full charge. Auto sleep mode for power saving after 30 minutes of no operation.
  • Space-Saving Tips: Using a full-size ergonomic keyboard mouse can enhance work efficiency, but it may occupy more workspace. The ergonomic keyboard dimensions: 20.75" L x 11" W, please measure your desk dimensions for better fit.

Other Options That Stood Out

Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.

ProtoArc Ergonomic Keyboard Mouse, EKM01 Plus Full Size Wireless Bluetooth Ergo Keyboard Mouse Combo, Cushioned Palm Rest, Split Design, Rechargeable,...

$99.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 28, 2025 1:45 am

Features

Warranty 1 Year
Color gray/black
  • Full-Size Ergonomic Comfort: Unlike standard keyboards, our wireless ergonomic keyboard is featured with full-size layout, curved and split keyframe design, helping to position your wrist and forearm in a more natural, relaxed typing posture. Premium ergonomic comfort that boosts productivity for all-day typing.
  • Cushioned Palm Rest: Curved wrist rest with soft memory foam layer offers typing comfort with more wrist support and less wrist bending. 4 Adjustable tilt legs position the keyboard at a perfect angle to keep your wrist relaxed and comfortable while sitting or standing.
  • Switch up to 3 Devices: Our wireless ergonomic keyboard and mouse can be connected up to 3 devices simultaneously through USB receiver or Bluetooth, seamlessly realize quick switch between 3 devices by just pressing a single button. Well compatible with Windows 7/8/10, Mac OS X 10.12, Android 4.3 or higher.
  • Precision Tracking: The contoured ergonomic mouse is designed with palm and thumb rest which provides better wrist support and keeps your hand in a natural position, effectively reduces the wrist tension and pain. 2000 DPI allows you to gain more precise control, forward/backward buttons provide more convenience for webpage browsing.
  • Type-C Charging: The ergonomic keyboard mouse combo are built-in 500mAh rechargeable lithium battery with 250 hours of standby time after 2 hours of full charge. Auto sleep mode for power saving after 30 minutes of no operation.
  • Space-Saving Tips: Using a full-size ergonomic keyboard mouse can enhance work efficiency, but it may occupy more workspace. The ergonomic keyboard dimensions: 20.75" L x 11" W, please measure your desk dimensions for better fit.

Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Keys Ergonomic Keyboard with Wrist Rest and 3-Level DPI Adjustable Wireless Ergonomic Mouse for...

$34.99 $45.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 28, 2025 1:45 am

Features

Warranty 12 Months Warranty
Color Black
Size Large
  • 【Wave Ergonomic Wireless Keyboard and Mouse Combo】The wireless keyboard features a wave key and wrist rest design that naturally fits your fingers and relieves wrist strain. The adjustable stand allows you to set the keyboard to the most comfortable height, making it ideal for long-term use. Note: The USB receiver is located on the back of the mouse.
  • 【Wireless Optical Mouse】The wireless mouse is designed with comfort in mind, featuring a contoured shape that fits snugly in the palm and complements the natural curve of your right hand. All controls are easily within reach. This mouse is equipped with forward and back functions, allowing you to navigate the web faster and more efficiently than ever before.
  • 【Plug-and-Play 2.4G Wireless Connection】One 2.4 GHz USB receiver can connect both the keyboard and mouse, or they can be used separately. Plug and play—no software download is required. The 2.4 GHz wireless connection offers a strong and reliable signal up to 33 feet (10 meters), without delays.
  • 【Automatic Power Saving Function】The ULSOU wireless keyboard and mouse combo features an automatic power-saving function. After 30 seconds of inactivity on the keyboard and 15 minutes of inactivity on the mouse, both devices enter sleep mode to conserve battery life. This greatly extends battery life, and any button press will activate the devices again. The keyboard requires 1 AA battery, and the mouse requires 1 AA battery. (batteries not included).
  • 【Wide Compatibility and Dual System Layout】This wireless keyboard and mouse combo is compatible with Windows XP/Vista/7/8/10/11, Mac, and other operating systems. It’s suitable for desktops, Chromebooks, PCs, laptops, and more. You can switch between Windows and macOS by pressing FN+Q or FN+W.
  • 【After-sales Service】We promise that all customers who purchase ULSOU wireless keyboards and mice will receive worry-free after-sales warranty service. Even if the return period on Amazon has passed, simply contact us, and we will provide a satisfactory solution as soon as possible.

ProtoArc Ergonomic Wireless Keyboard Mouse, EKM01 Plus Full Size Ergo Bluetooth Keyboard Mouse Combo, Split Design, Wrist Rest, Multi-Device, Rechargeable,...

$71.24 $99.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 28, 2025 1:45 am

Features

Part Number EKM01 Plus
Model EKM01 Plus
Warranty 1 year warranty
Color Black
  • Full-size Ergonomic Design: The wireless ergonomic keyboard features with full size layout, curved and split keyframe design, which helps to position your wrist and forearm in a more natural, relaxed posture. Scooped keys perfectly match the shape of your fingertips, offering quick response with every keystroke. Premium comfort and productivity for all-day typing.
  • Cushioned Wrist Rest: Curved wrist rest with soft memory foam layer offers typing comfort with more wrist support, less wrist bending compared to other standard keyboards without wrist rest. Adjustable tilt legs design positions the keyboard at a perfect angle to keep your wrist in a relaxed and comfortable typing posture whether seated or standing.
  • Switch up to 3 Devices: Conveniently connect with USB receiver or Bluetooth, the ergonomic wireless keyboard mouse combo supports up to 3 devices simultaneously and effortlessly realize quick switch between 3 devices by pressing a single button. The ergonomic wireless combo is well compatible with Windows 7/8/10, Mac OS X 10.12, Android 4.3 or higher.
  • Ergonomic Sculpted Shape: The wireless ergonomic mouse is designed with palm and thumb rest that provides better wrist support and keeps your hand in a natural position, effectively reduces the wrist strain and pain. 2000 DPI allows you to gain more precise control. Added forward/backward buttons provide more convenience when webpage browsing.
  • Type-C Rechargeable Design: Both the keyboard and the mouse are built in 500mAh lithium battery, easily recharged through the included Type-C cable. Auto sleep mode for power saving after 30 minutes of no operation.
  • Kindly Note: Using a full-size ergonomic keyboard mouse can enhance work efficiency, but it may occupy more workspace. The full-size ergonomic keyboard is 20.75 inch long, 11 inch wide, please measure the desk dimensions before ordering for better fit.

Logitech Wave Keys MK670 Combo, Wireless Ergonomic Keyboard with Signature M550 L Wireless Mouse, Comfortable Natural Typing, Bluetooth, Logi Bolt, for...

$79.99 $89.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 28, 2025 1:45 am

Features

Part Number 920-012060
Model 920-012060
Warranty 1 Year Limited Hardware Warranty
Color Graphite
Release Date 2023-10-15T00:00:01Z
Language English
  • Meet the comfort combo: Get comfier with the Wave Keys Ergonomic Wireless Keyboard paired with the Signature M550 L Wireless Mouse - a great fit for medium- to large-sized hands
  • Compact keys: Wave Keys’ compact size allows you to bring your mouse closer to your body, resulting in a more natural shoulder position compared to a full size keyboard
  • Type in comfort all day long: The wavy design of this compact keyboard places your hands, wrists and forearms in a natural typing position for all-day comfort
  • More palm support, less pressure: A cushioned palm rest with memory foam gives you more wrist support throughout the day (1)
  • Less noise, more focus: On top of its sculpted design and rubber grip, this quiet mouse uses SilentTouch technology to make workdays more peaceful with 90% less click noise (7)
  • Scroll smarter: Scroll through documents line by line, or fly effortlessly through long web pages with SmartWheel
  • Smoother days, your Way: Personalize your Wave Keys experience using the Logi Options+ App, where you can choose shortcuts that save time and keep your work flowing (2)
  • Connect the keyboard via Bluetooth or Logi Bolt and use Easy-Switch* to toggle between PC, tablet, and phone (Windows/macOS/iPadOS/ChromeOS); *not-applicable for Signature M550 L mouse
  • Plastic parts in Wave Keys and Signature M550 L include certified post-consumer recycled plastic (Keyboard: 61%(5), Mouse: 65%(6))
  • In case of wireless keyboard or combo (keyboard and mouse), the USB receiver is usually provided either inside the mouse (under the battery cover) or attached within the product packaging

Ergonomic Wireless Keyboard and Mouse Combo, 2.4G Full Size Wave Key Board with Cushioned Palm Rest, Natural Typing, 3 DPI Adjustable Mouse, USB-A & C for...

$49.99 $59.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 28, 2025 1:45 am

Features

Warranty 1 Year
Color Black
Size Full Size
  • Premium Comfort & Craftsmanship: Sink into the luxury of a silky-soft faux lambskin palm rest with a refined matte finish. Unlike fabric, this sweat-proof leatherette stays clean, durable, and easy to maintain—crafted to impress, built to last.
  • Wave Keys & Healthy Ergonomics: Dual-angle tilt legs and contoured wave-shaped keys follow natural finger curves, promoting healthy wrist posture and reducing typing errors. Stay comfortable and accurate, whether sitting or standing.
  • 10M Keystroke Durability: Built to handle 10 million keystrokes—twice the life of standard keyboards (5M). A smarter long-term investment that saves on replacements. (Peace of mind: 30-day return + 1-year replacement.)
  • Sculpted Mouse & Smarter Shortcuts: Ergonomic mouse with 3 adjustable DPI settings (800/1200/1600) adapts to work or browsing. 9 shortcut keys streamline apps, media, and volume for faster productivity and smoother workflows.
  • Universal Compatibility: One 2.4GHz USB receiver (33ft range) connects both keyboard and mouse. USB-A & C combo works with 99% of devices—PCs, laptops, tablets, desktops, and Macs. Switch between Windows/macOS instantly with FN+Q/W. Plug and play.
  • Sleek Design & Gift-Ready: A modern, aerodynamic form that elevates any workspace. Stylish yet practical, it also makes a thoughtful gift for professionals, coworkers, or loved ones—ideal for Christmas, birthdays, or office gifting.

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