Top 5 Best Ergonomic Mice Under $50
Choosing a in 2025 isn’t simple.
We looked at reviews, specs, and overall performance to narrow it down.
One stood out across the board.
1
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
9.8
Amazon.com
2
TECKNET Ergonomic Mouse Wireless, Rechargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB Vertical Mouse Wireless for Laptop, 5...
9.8
Amazon.com
3
TECKNET Ergonomic Mouse, Rechargeable Wireless Bluetooth Mouse (BT 5.0/5.0+2.4G), Vertical Mouse with Volume Knob, Quiet Clicks, Cordless Mice 6 Adjustable...
9.4
Amazon.com
4
TECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 12 Months...
9.4
Amazon.com
5
TECKNET USB Wired Mouse, 6-Button Corded Computer Mouse with 4 Adjustable DPI, Optical Computer Mice with Ergonomic Design and 5FT Cord for Laptop,...
9.3
Amazon.com
Top Pick
This is the product that stood out most — for performance, price, and overall value.
TECKNET Ergonomic Mouse Wireless, Rechargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB Vertical Mouse Wireless for Laptop, 5...
$24.99
PRIMEPRIME
in stock
Amazon.com
Features
| Model | TK-MS007 |
| Warranty | 36 Months |
| Color | Black |
- Ergonomic Design: This ergonomic mouse promotes a natural wrist and arm position, minimizing hand fatigue from prolonged use. With a vertical layout, the vertical mouse aids in maintaining a comfortable posture, reducing shoulder and neck strain.
- Long-Lasting & Rapid Charging: Equipped with a 600mAh battery, the ergonomic mouse wireless fully charges in 1.5 hours via Type-C (cable included). The vertical mouse delivers a 2-month runtime per charge(depending on the actual frequency of use).
- Stable Wireless Vertical Mouse: 2.4 GHz technology ensures reliable 10m connectivity with zero interference. Plug-and-play via nano USB receiver (no drivers required). Ergonomic design maintains seamless productivity for office/remote professionals.
- Silent Ergonomic Mouse Wireless: Silent-click tech eliminates noise in shared spaces (libraries/offices/homes). The vertical mouse is perfect for mobile workers in noise-sensitive environments, blending ergonomic comfort with wireless convenience. Note: The left and right click keys of this silent mouse are silent, and the other auxiliary keys are not silent.
- Adjustable DPI Vertical Mouse: 5-step 4800-800 DPI adapts to tasks/habits. Tru-Wave optical tracking surpasses traditional mice with enhanced sensitivity, ensuring precision on multiple surfaces (excluding glass). Professional-grade responsiveness for graphic design/office workflows.
- Wide Compatibility: 2.4GHz ergonomic mouse wireless ensures stable connectivity with USB-A devices (desktops/laptops/PCs). The vertical mouse seamlessly fits most computer models featuring USB-A port interfaces but excludes USB-C.
- Power Saving Mode: The ergonomic mouse wireless Features an automatic sleep mode that automatically turns off and saves power after 8 minutes of inactivity—click any button to reactivate the vertical mouse.
More Worth Considering
Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.
TECKNET Ergonomic Mouse Wireless, Rechargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB Vertical Mouse Wireless for Laptop, 5...
$24.99
PRIMEPRIME
in stock
Amazon.com
Features
| Model | TK-MS007 |
| Warranty | 36 Months |
| Color | Black |
- Ergonomic Design: This ergonomic mouse promotes a natural wrist and arm position, minimizing hand fatigue from prolonged use. With a vertical layout, the vertical mouse aids in maintaining a comfortable posture, reducing shoulder and neck strain.
- Long-Lasting & Rapid Charging: Equipped with a 600mAh battery, the ergonomic mouse wireless fully charges in 1.5 hours via Type-C (cable included). The vertical mouse delivers a 2-month runtime per charge(depending on the actual frequency of use).
- Stable Wireless Vertical Mouse: 2.4 GHz technology ensures reliable 10m connectivity with zero interference. Plug-and-play via nano USB receiver (no drivers required). Ergonomic design maintains seamless productivity for office/remote professionals.
- Silent Ergonomic Mouse Wireless: Silent-click tech eliminates noise in shared spaces (libraries/offices/homes). The vertical mouse is perfect for mobile workers in noise-sensitive environments, blending ergonomic comfort with wireless convenience. Note: The left and right click keys of this silent mouse are silent, and the other auxiliary keys are not silent.
- Adjustable DPI Vertical Mouse: 5-step 4800-800 DPI adapts to tasks/habits. Tru-Wave optical tracking surpasses traditional mice with enhanced sensitivity, ensuring precision on multiple surfaces (excluding glass). Professional-grade responsiveness for graphic design/office workflows.
- Wide Compatibility: 2.4GHz ergonomic mouse wireless ensures stable connectivity with USB-A devices (desktops/laptops/PCs). The vertical mouse seamlessly fits most computer models featuring USB-A port interfaces but excludes USB-C.
- Power Saving Mode: The ergonomic mouse wireless Features an automatic sleep mode that automatically turns off and saves power after 8 minutes of inactivity—click any button to reactivate the vertical mouse.
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | AK-98ANWVM-UBA |
| Model | AK-98ANWVM-UBA |
| Color | Black |
| Is Adult Product |
- Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
- 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
- Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
- Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
- Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.
TECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 12 Months...
$26.99
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | TK-MS007 |
| Model | TK-MS007 |
| Warranty | 3 years |
| Color | Black |
- 【Seamless Switching Between Three Devices】The ergonomic mouse features Bluetooth (5.0/3.0) and 2.4GHz USB A modes for connectivity. When connected via Bluetooth, The vertical mouse can effectively reduces the usage of your USB-A port (Bluetooth mode can connect to two devices simultaneously), which is convenient for devices without USB ports. To switch to 2.4GHz mode, simply plug in the USB receiver for quick connection without the need for additional software installation. With just a press of a button, you can easily switch between these two modes, enhancing your work efficiency (Note: The 2.4GHz receiver is built into the bottom of the mouse).
- 【Higher DPI & 6 Adjustable Levels】This vertical ergonomic mouse is equipped with a high-performance chip and features 6 adjustable DPI levels (4800/3200/2400/1600/1200/800) to meet your daily needs. wireless mouse upgraded technology allows this ergonomic mouse to operate smoothly on different types of surfaces. When changing the DPI, the light will flash, with the number of flashes corresponding to the DPI level.
- 【Silent Mouse】This computer mouse operates quietly, allowing for usage even in quiet environments like libraries. Additionally, the vertical mouse provides nearly silent clicks, helping avoid disturbances to others and ensuring your work or study remains undisturbed (Note: Only the left and right click buttons of the mouse are silent; other function buttons are not silent).
- 【Ergonomic Design】The wireless mouse's ergonomic design offers ultimate comfort by placing your palm at a near-vertical angle on the desktop, reducing pressure and pain on your wrist caused by prolonged inverted mouse usage (Note: Mouse is designed for right-handed use only).
- 【Broad Compatibility and Low Battery Warning】The wireless computer mouse is compatible with various devices, including Windows, Mac, Chrome, and Linux laptops (side buttons are not compatible with macOS). Additionally, this bluetooth mouse for laptops automatically enters deep sleep mode after approximately 10-30 minutes of inactivity to conserve power; you can awake it by pressing the right or left button. Note: We recommend using branded batteries to ensure the mouse's longevity. When the battery is low, the LED light will blink (Requires 2 AAA batteries, not included).
- 【36 MONTHS WARRANTY】If you encounter any problems in using the product, please feel free to contact our professional customer service team, enjoying TECKNET 36 Months Warranty (Registered Only).
TECKNET Ergonomic Mouse, Rechargeable Wireless Bluetooth Mouse (BT 5.0/5.0+2.4G), Vertical Mouse with Volume Knob, Quiet Clicks, Cordless Mice 6 Adjustable...
$18.99
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | TK-MS042 |
| Model | TK-MS042 |
| Warranty | 3 years |
| Color | Black |
- One-Click Multi-Device Control: This Bluetooth mouse enables seamless switching across 3 devices with advanced 2.4G + Dual Bluetooth 5.0 connectivity. Easily toggle between your computer (via USB-A receiver), smartphone, and tablet with just one click—no need for repeated pairing. Perfect for multitaskers who work, browse, and stream without interruption.
- Media Control at Your Fingertips: Featuring a dedicated media control knob, you can instantly adjust volume and play/pause directly—all without lifting your fingers off the TECKNET optical wireless mouse. Enjoy seamless control that keeps you in the flow, whether you're working or relaxing.
- Ergonomic Comfort: Say goodbye to wrist strain and hello to pain-free productivity! This ergonomic vertical mouse features a 57° tilt design and integrated palm support, this ergonomic mouse keeps your hand in a natural, relaxed position, helping prevent wrist fatigue and carpal tunnel syndrome—perfect for long hours of work.
- Fast Charging & Long Battery Life: Enjoy up to 60 days of use on just 2.5 hours of charging with our long-lasting rechargeable wireless mouse. The 500mAh battery and Type-C fast charging (cable included) eliminate the hassle of battery swaps or interruptions.
- Silent Click: Engineered with ultra-quiet button mechanisms, this silent USB computer mouse offers soft, tactile clicks without distracting noise. Perfect for libraries, late-night work, important meetings, and shared spaces—stay focused and productive without disturbing others in any environment.
- 36-Month Warranty: If you experience any issues while using the product, our dedicated customer service team is here to assist you promptly and professionally. Enjoy peace of mind with the TECKNET 36-Month Warranty (Registered Customer Only).
TECKNET USB Wired Mouse, 6-Button Corded Computer Mouse with 4 Adjustable DPI, Optical Computer Mice with Ergonomic Design and 5FT Cord for Laptop,...
$9.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | 843663 |
| Model | TK-EMS014 |
| Color | GRAY |
- 【High Precision and Durability】: TECKNET Tru-Wave technology wired computer mouse provides precise, intelligent cursor control and tracking on many surface types, even on smooth surfaces with glass. Tested for over 6 million keystrokes, the wired mouse ensures responsive clicks and a longer lifespan for daily use.
- 【4 Adjustable DPI and 6 Buttons】: 4-level DPI settings (1000/1600/3200/6400) to meet your needs both in home and office. 6 buttons enable superior productivity and efficiency to meet all your computer needs. Moving quickly between documents or browsing your favorite Web sites is a breeze with large, easy-to-reach Back/Forward buttons.
- 【Ergonomic Design】: The shaped design and soft rubber grips conform to the hand and are designed to be comfortable to hold. The compact size enables it to be able to be taken wherever desired for use on the computer whether at home, at work or anywhere else.
- 【Plug and Play】: Simply plug in the USB cable to power your mouse, eliminates the trouble of replacing batteries. No software or downloads required. The 5FT of USB cable is the perfect length for a USB wired mouse and adapts to almost any computer setup with no lag.
- 【Wide Compatibility】：Compatible with Windows 2000,2003, XP, VISTA, 7, 8, 10, 11 and Chromebook, Mac (side buttons not work on Mac).
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