Top 5 Best Left-Handed Ergonomic Mice

With so many choices out there, picking the right takes time.

After reviewing a wide range of options, some clear standouts emerged.

The best option wasn’t the most expensive — but it delivered where it counts.

1
MEETION Left-Handed Mouse, Ergonomic Mouse Wireless Vertical Mouse, RGB Rechargeable Mice for Bluetooth(5.2 + 3.0) & USB-A with Type-c Adapter 4 Adjustable DPI for Mac/Windows/PC/Tablet/iPad Purple
MEETION Left-Handed Mouse, Ergonomic Mouse Wireless Vertical Mouse, RGB Rechargeable Mice for Bluetooth(5.2 + 3.0) & USB-A with Type-c Adapter 4 Adjustable...
9.5
Amazon.com
2
Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Left Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC - Graphite
Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Left Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop,...
9.5
Amazon.com
3
SUNGI Left-Handed Mouse,2.4GHz Ergonomic Vertical DPI 800/1200/1600 Wireless Mouse with USB Receiver for Left Hand,Black
SUNGI Left-Handed Mouse,2.4GHz Ergonomic Vertical DPI 800/1200/1600 Wireless Mouse with USB Receiver for Left Hand,Black
9.4
Amazon.com
4
KUNSI Left Handed Mouse, 2.4G Wireless Left Handed Ergonomic Mouse with 800/1200/1600 Adjustable DPI, 6 Buttons Wireless Vertical Mouse for MacBook/Laptop/PC/Desktop-Black
KUNSI Left Handed Mouse, 2.4G Wireless Left Handed Ergonomic Mouse with 800/1200/1600 Adjustable DPI, 6 Buttons Wireless Vertical Mouse for...
9.4
Amazon.com
5
ELECOM Left Hand Bluetooth Wireless Ergonomic Mouse, Silent Click, 2000DPI, 5 Buttons, Optical Sensor, Compatible with PC, Mac, Laptop, EX-G, Lsize Black (M-XGL31BBSKBK)
ELECOM Left Hand Bluetooth Wireless Ergonomic Mouse, Silent Click, 2000DPI, 5 Buttons, Optical Sensor, Compatible with PC, Mac, Laptop, EX-G, Lsize Black...
8.9
Amazon.com

Top Pick

This is the product that stood out most — for performance, price, and overall value.

Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Left Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop,...

$79.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 17, 2025 12:45 am

Features

Part Number 910-006467
Model 910-006467
Warranty 1 Year Limited Hardware Warranty
Color GRAPHITE
Release Date 2022-04-19T00:00:01Z
Size Mouse
  • Lift yourself up: When desk work gets you down, lift yourself up with this Logitech Wireless Ergonomic Mouse - a great fit for small to medium left hands
  • Raise your hand into comfort with this computer mouse wireless: Rest on Lift upright mouse throughout the day with a softly textured grip and snug thumb rest for level-above coziness
  • 57 degrees of soothe: This wireless ergonomic mouse promotes a more natural posture in the forearm for comfort and productivity, for day-long comfort and productivity
  • Relax into focus: Settle into work with this ergonomic wireless mouse featuring easy-to-reach customizable buttons, whisper-quiet clicks, and a SmartWheel for smooth, seamless scrolling
  • Ergo-certified: This wireless vertical mouse has been designed, developed, tested, and approved according to criteria set out by leading ergonomists

Top Picks Compared

Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.

Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Left Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop,...

$79.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 17, 2025 12:45 am

Features

Part Number 910-006467
Model 910-006467
Warranty 1 Year Limited Hardware Warranty
Color GRAPHITE
Release Date 2022-04-19T00:00:01Z
Size Mouse
  • Lift yourself up: When desk work gets you down, lift yourself up with this Logitech Wireless Ergonomic Mouse - a great fit for small to medium left hands
  • Raise your hand into comfort with this computer mouse wireless: Rest on Lift upright mouse throughout the day with a softly textured grip and snug thumb rest for level-above coziness
  • 57 degrees of soothe: This wireless ergonomic mouse promotes a more natural posture in the forearm for comfort and productivity, for day-long comfort and productivity
  • Relax into focus: Settle into work with this ergonomic wireless mouse featuring easy-to-reach customizable buttons, whisper-quiet clicks, and a SmartWheel for smooth, seamless scrolling
  • Ergo-certified: This wireless vertical mouse has been designed, developed, tested, and approved according to criteria set out by leading ergonomists

MEETION Left-Handed Mouse, Ergonomic Mouse Wireless Vertical Mouse, RGB Rechargeable Mice for Bluetooth(5.2 + 3.0) & USB-A with Type-c Adapter 4 Adjustable...

$24.98
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 17, 2025 12:45 am

Features

Model MEETION-BTM010
Warranty 1 year manufacturer
Color Purple (for large Left-hands)
Size Left-Handed
  • LEFT-HANDED MOUSE ERGONOMIC MOUSE: BTM010 mouse is designed with a unique vertical shape that reduces the strain on your wrist and forearm, providing a more comfortable and natural grip. It can help improve your posture by reducing the strain on your wrist and forearm, promoting a more natural and comfortable position.
  • VERSATILE CONNECTIVITY & COMPATIBILITY: With Bluetooth 5.0 + 3.0, and 2.4G wireless connections, allowing for easy connectivity to multiple devices, making it an excellent tool for productivity on the go. It is compatible with a range of operating systems, including Windows, Mac, and Linux, making it a versatile tool for a wide range of users. Please note: The USB-C is not a receiver and cannot be used on its own, it is an adapter that needs to be plugged into a USB-A receiver in order to work.
  • 【RGB LIGHTING & RECHARGEABLE】 BTM010 Bluetooth mouse showcases RGB lighting, with a spectrum of colors and effects that suit your unique style and mood. It is also equipped with a rechargeable battery, eliminating the need for disposable batteries and reducing environmental impact.
  • ADJUSTABLE DPI & FORWARD/BACKWARD BUTTONS: With 4 adjustable DPI settings (800-1200-1800-2400), our mouse provides precise and accurate tracking, perfect for gaming, design work, and other tasks. The mouse is designed with easy-to-reach forward and backward buttons, allowing you to quickly navigate through web pages, documents, and other content.
  • SMOOTH SCROOLING & DURABLE DESIGN: BTM010 mouse features a smooth scrolling wheel that enables you to quickly and effortlessly scroll through long documents and web pages. Our mouse is built to last with high-quality materials that provide a sturdy and reliable design.

KUNSI Left Handed Mouse, 2.4G Wireless Left Handed Ergonomic Mouse with 800/1200/1600 Adjustable DPI, 6 Buttons Wireless Vertical Mouse for...

$13.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 17, 2025 12:45 am

Features

Warranty 1 Year Warranty
  • 【Left-Handed Ergonomic Mouse】The Ergonomic Vertical Mouse is designed special for left-handed users, the vertical design conforms to neutral handshake position when you holding the mouse, allowing the arm and wrist rest naturally, relieve wrist pain and discomfort during work.
  • 【2.4G Wireless Connection】The ergonomic mouse has built in 2.4GHz USB wireless connection, just plug and play, offering stable and quick performance with max working distance of 10M.
  • 【Adjustable DPI】The vertical mouse has 800 / 1200 / 1600 three levels of adjustable DPI, you can choose the mouse sensitivity according to your needs.
  • 【Convenient with Next/Previous Buttons 】The ergo mouse has added Next and Previous buttons provides convenience with web page browsing(Note: The forward/back buttons are unavailable on Mac OS systems).
  • 【Packing List 】: One Wireless Vertical Ergonomic Mouse (2 AAA batteries not included), One 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual.

SUNGI Left-Handed Mouse,2.4GHz Ergonomic Vertical DPI 800/1200/1600 Wireless Mouse with USB Receiver for Left Hand,Black

$16.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 17, 2025 12:45 am

Features

Part Number S8
Warranty 1 year manyfacturer
Color Black
Size 4.13 x 3.15 x2.75 inch
  • 【Ergonomic Vertical Design】Encourage healthy natural “handshake” wrist and palm position for the most comfortable grip, less wrist strain. The ergonomically- designed thumb rests and grips fit the contour of your palm for maximum comfort, perfect for small hands.The surface of the mouse is sprayed with rubber oil, which is very comfortable to touch.This mouse is very suitable for people with RSI or customers who use the mouse for a long time.
  • 【Easy to use】Just plug the included USB receiver into the USB port of your computer, no other additional software needed(the receiver is at the bottom of the mouse). New to Vertical Mouse will adapt to for a while, after using you will love it.
  • 【Automatic sleep function】 The sleeping function is for saving energy, it goes to sleep when you are not using it for 10 minutes, and you only need to click any button on the mouse once, it should be back to work. When the receiver is recognized by the computer, it's connected to the mouse, and then the LED of the mouse will light up.
  • 【3 Adjustable DPI】DPI800/1200/1600,the higher DPI, the faster the cursor on your screen will move.adjust DPI according to your needs.Added next / previous buttons provide convenience when web surfing.
  • 【Wide Compatibility】Compatible with Windows 7/10/XP/CE/vista, Windows2000,Android ,Vista and Linux etc(NOT FOR MAC OS).We offer 12 months warranty for our Procuct,Please feel free to contact us, if you have any questions.

ELECOM Left Hand Bluetooth Wireless Ergonomic Mouse, Silent Click, 2000DPI, 5 Buttons, Optical Sensor, Compatible with PC, Mac, Laptop, EX-G, Lsize Black...

$29.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 17, 2025 12:45 am

Features

Part Number M-XGL31BBSKBK
Model M-XGL31BBSKBK
Color Left Hand_Black
Size Large
  • ERGONNOMIC SHAPE - Particular about height and angle can be used in a relaxed posture from the palm to the wrist and arm.
  • LEFT HANDED MOUSE - Design exclusively for the left hand, with the left click located on the right side, allowing the index finger to perform the main operations.
  • SILENT CLICK SWITCH - A Silent switch does not make a ticking sound. You can use mouse during the meeting, early in the morning and night work, even when you work at home, without worrying about the sounds around you.
  • CUSTOMIZABLE BUTTONS - The button function assignment ELECOM Mouse Assistant software, which can be downloaded from the website, allows you to customize the buttons to your preferred functions.
  • DIMENSION & WEIGHT - 3.1in x 4.7in x 2.3in, Weight: 3.5oz
  • PRODUCT WARRANTY - This product has a 2-year warranty. In the unlikely event of a product defect, we offer a product warranty for quality issues for your convenience. Within 2 years of purchase, we will replace the defective product by applying for a return or exchange using the return/exchange request form on our website(elecomusa dot com). For more information about our warranty, please visit our website.

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