Best Vertical Ergonomic Keyboards

Choosing a in 2025 isn’t simple.

Some models looked good on paper, but only a few delivered in real use.

The best option wasn’t the most expensive — but it delivered where it counts.

1
Perixx Periduo-605, Wireless Ergonomic Split Keyboard and Vertical Mouse Combo, Adjustable Palm Rest and Membrane Low Profile Keys, Black, US English Layout (11633)
Perixx Periduo-605, Wireless Ergonomic Split Keyboard and Vertical Mouse Combo, Adjustable Palm Rest and Membrane Low Profile Keys, Black, US English Layout...
10
Amazon.com
2
MEETION Ergonomic Wireless Keyboard and Mouse, Ergo Keyboard with Vertical Mouse, Split Cushioned Wrist Palm Rest, Natural Typing, Rechargeable, Full Size, Windows/Mac/Computer/Laptop, Black DirectorC
MEETION Ergonomic Wireless Keyboard and Mouse, Ergo Keyboard with Vertical Mouse, Split Cushioned Wrist Palm Rest, Natural Typing, Rechargeable, Full Size,...
10
Amazon.com
3
2.4GHz Wireless Vertical Ergonomic Mouse and Keyboard Combo Ultra-Thin Portable Size for PC Desktop Computer Laptop Mac Tablet
2.4GHz Wireless Vertical Ergonomic Mouse and Keyboard Combo Ultra-Thin Portable Size for PC Desktop Computer Laptop Mac Tablet
9.6
Amazon.com
4
Logitech ERGO K860 Wireless Ergonomic Keyboard & Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons - Graphite
Logitech ERGO K860 Wireless Ergonomic Keyboard & Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons -...
9.3
Amazon.com
5
Perixx PERIDUO-512B US, Wired Ergonomic Keyboard and Vertical Mouse Combo - USB - Black - US English
Perixx PERIDUO-512B US, Wired Ergonomic Keyboard and Vertical Mouse Combo - USB - Black - US English
8.4
Amazon.com

Top Pick

This is the product that stood out most — for performance, price, and overall value.

MEETION Ergonomic Wireless Keyboard and Mouse, Ergo Keyboard with Vertical Mouse, Split Cushioned Wrist Palm Rest, Natural Typing, Rechargeable, Full Size,...

$69.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 13, 2025 1:45 am

Features

Part Number DirectorC
Model DirectorC
Warranty 1 year manufacturer
Color Black
Size Large
  • 【DIRECTOR-C SPLIT KETBOARD】Designed to minimize strain and discomfort in your hands, wrists, and arms, this keyboard is split into two halves, allowing each hand to type at a comfortable angle and distance, so you can say goodbye to excessive reaching and twisting. Please note: The USB-C is not a receiver and cannot be used on its own, it is an adapter that needs to be plugged into a USB-A receiver in order to work. (Connection distance within 33 feet)
  • 【LARGE SIZE STANDARD ERGONOMIC AND FULL SIZE LAYOUT】Designed with a concave curve, which conforms to the natural shape of the hands and fingers, reducing strain and fatigue. In addition, each key is slightly angled to promote a more natural typing motion and further alleviate stress on your fingers, hands, and wrists. Keyboard(19.09*10.04*1.83inch)Mouse (2.87*4.09*2.28inch)
  • 【PILLOWED WRIST REST】Featured a pillowed palm rest, providing support and comfort for the hands and wrists. Made of a soft, non-slip material, preventing slippage and enhancing stability during typing. It reduce the risk of developing musculoskeletal disorders associated with prolonged keyboard use.
  • 【VERTICAL ERGONOMIC MOUSE】Unique vertical design offers optimal ergonomics, with adjustable DPI settings (800/1200/1600/2400)to suit various tasks and preferences, ensuring accuracy and speed when needed, a silent switch, and a side-scrolling wheel, catering to all your needs. The mouse and keyboard share a common USA-A receiver.
  • 【RECHARGEABLE AND LONG LASTING】 Featuring a 500mAh and 500mAh rechargeable battery in both the keyboard and mouse, providing long-lasting performance for extended use. The battery holds power for up to 1-2 months of usage on a single full charge. You can focus on work and worry less about charging. (Charge your keyboard and mouse before you use them. We recommend using the 5V 1A charging specification.).

More Worth Considering

Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.

MEETION Ergonomic Wireless Keyboard and Mouse, Ergo Keyboard with Vertical Mouse, Split Cushioned Wrist Palm Rest, Natural Typing, Rechargeable, Full Size,...

$69.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 13, 2025 1:45 am

Features

Part Number DirectorC
Model DirectorC
Warranty 1 year manufacturer
Color Black
Size Large
  • 【DIRECTOR-C SPLIT KETBOARD】Designed to minimize strain and discomfort in your hands, wrists, and arms, this keyboard is split into two halves, allowing each hand to type at a comfortable angle and distance, so you can say goodbye to excessive reaching and twisting. Please note: The USB-C is not a receiver and cannot be used on its own, it is an adapter that needs to be plugged into a USB-A receiver in order to work. (Connection distance within 33 feet)
  • 【LARGE SIZE STANDARD ERGONOMIC AND FULL SIZE LAYOUT】Designed with a concave curve, which conforms to the natural shape of the hands and fingers, reducing strain and fatigue. In addition, each key is slightly angled to promote a more natural typing motion and further alleviate stress on your fingers, hands, and wrists. Keyboard(19.09*10.04*1.83inch)Mouse (2.87*4.09*2.28inch)
  • 【PILLOWED WRIST REST】Featured a pillowed palm rest, providing support and comfort for the hands and wrists. Made of a soft, non-slip material, preventing slippage and enhancing stability during typing. It reduce the risk of developing musculoskeletal disorders associated with prolonged keyboard use.
  • 【VERTICAL ERGONOMIC MOUSE】Unique vertical design offers optimal ergonomics, with adjustable DPI settings (800/1200/1600/2400)to suit various tasks and preferences, ensuring accuracy and speed when needed, a silent switch, and a side-scrolling wheel, catering to all your needs. The mouse and keyboard share a common USA-A receiver.
  • 【RECHARGEABLE AND LONG LASTING】 Featuring a 500mAh and 500mAh rechargeable battery in both the keyboard and mouse, providing long-lasting performance for extended use. The battery holds power for up to 1-2 months of usage on a single full charge. You can focus on work and worry less about charging. (Charge your keyboard and mouse before you use them. We recommend using the 5V 1A charging specification.).

Perixx Periduo-605, Wireless Ergonomic Split Keyboard and Vertical Mouse Combo, Adjustable Palm Rest and Membrane Low Profile Keys, Black, US English Layout...

$69.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 13, 2025 1:45 am

Features

Part Number 11633
Model PERIDUO-605
Warranty 12-Month-Limited-Warranty
Color Black
Release Date 2023-10-10T00:00:01Z
  • ALL-IN-ONE - Ergonomic keyboard and mouse value kit; Designed specifically in order to reduce the pressure from your hands while computing and give you the benefit to type relaxed and effortlessly
  • ONE RECEIVER FOR TWO DEVICES - 2-in-1 USB Nano Receiver for mouse and keyboard (stored inside the keyboard); 30 Feet operating range; require 4 x AAA for operation (Batteries are not included)
  • SPLIT-KEY KEYBOARD - A one-piece design that simply separates the keys into two groups for the left and right hand to reduce bending your wrists outward while typing; Designed specifically in order to reduce the pressure from your hands while computing and give you the benefit to type relaxed and effortlessly
  • VERTICAL MOUSE - Wireless ergonomic vertical design with 5-button and adjustable 1000 /1500/2000 DPI Resolution
  • SYSTEM REQUIREMENTS - Windows 7, 8, 10; Easy installation with Plug and Play feature, no drivers needed; Package Includes: 1 Keyboard, 1 Mouse, 1 Armrest, 1 Movable Magnet (for height adjustment), manual, and 12-month limited warranty
  • Ergonomic compact keyboard and mouse set - valuable compact desktop set that was specially developed for the pressure of your hands during of computer operations and give you the advantage of being effortless and relaxed

2.4GHz Wireless Vertical Ergonomic Mouse and Keyboard Combo Ultra-Thin Portable Size for PC Desktop Computer Laptop Mac Tablet

$42.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 13, 2025 1:45 am

Features

Warranty 1 year
Color black
Size A
  • ERGONOMIC DESIGN: The mouse scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain. The keyboard slope angle for comfortable use feeling, your hand will Not feel tired after using a while time. A good choice for people who work with the PC for a long time.
  • WIRELESS CONNECTIVITY: 2.4 GHz wireless technology with approximately 33 feet (10 meters) operating distance; One Nano USB receiver for both mouse and keyboard; You can find the receiver in the receiver compartment located on the backside of the keyboard.
  • FULL SIZE & ULTRA-THIN KEYBOARD: 17.72x5.91x1.57in with 101 Keys,ultra-thin enough to put it into your handbag or suitcase. Scissor-key-switch provide smooth typing and sensitive response, lowest volume keyboard keys and quiet mouse button.
  • 3 Adjustable DPI: 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Wide Compatibility: This wireless keyboard and mouse is support to work with windows, xp, mac os, vista, linux and other systems, but not suitable for ios system; The 12 hot keys on the keyboard are compatible windows system only.

Logitech ERGO K860 Wireless Ergonomic Keyboard & Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons -...

$219.98
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 13, 2025 1:45 am

Features

Model ERGO K860
Color Graphite
  • Product 1: Improved Typing Posture: Type more naturally with a curved, split keyframe and reduce muscle strain on your wrists and forearms thanks to the sloping keyboard design
  • Product 1: Pillowed Wrist Rest: Curved wrist rest with memory foam layer offers typing comfort with 54 per cent more wrist support; 25 per cent less wrist bending compared to standard keyboard without palm rest
  • Product 1: Perfect Stroke Keys: Scooped keys match the shape of your fingertips so you can type with confidence on a wireless keyboard crafted for comfort, precision and fluidity
  • Product 1: Adjustable Palm Lift: Whether seated or standing, keep your wrists in total comfort and a natural typing posture with ergonomically-designed tilt legs of 0, -4 and -7 degrees
  • Product 2: Lift yourself up: When the desk life gets you down, lift yourself up with Logitech Lift Vertical Ergonomic Mouse - a great fit for small to medium right hands
  • Product 2: Raise your hand into comfort: Rest on Lift upright mouse throughout the day, with a softly textured grip and snug thumb rest for level-above cosiness
  • Product 2: 57 degrees of sooooothe: Lift’s vertical shape helps wrists feel like “ahhh” at work, and promotes a more natural posture in the forearm, for day-long comfort and productivity
  • Product 2: Relax into focus: Settle into work with a cordless mouse featuring easy-to-reach customisable buttons, whisper-quiet clicks and a SmartWheel for smooth, seamless scrolling

Perixx PERIDUO-512B US, Wired Ergonomic Keyboard and Vertical Mouse Combo - USB - Black - US English

$59.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 13, 2025 1:45 am

Features

Part Number PD-512BUS-12174
Model PD-512BUS-12174
Warranty 12 Months Limited Warranty
Color Black
Release Date 2024-04-07T00:00:01Z
  • ERGONOMIC DESIGN - Split-key and 3D Curve promote a natural typing position; Integrated palm rest to support your palm and wrist for comfortable typing
  • ERGO MOUSE - Natural ergonomic vertical mouse designed for right hands that promotes natural hand posture while using the mouse for long-lasting comfort
  • COMFORTABLE KEYSTROKES - Membrane keys with long travel distances minimize pressure with every keystroke and provide a more comfortable typing experience
  • COMFORTABLE CURSOR CONTROL - Recommended for users with Repetitive Strain Injuries RSI User and users who work particularly long periods on the computer; DPI button supports easy switching between 1000 and 1600 DPI levels.
  • SYSTEM REQUIREMENTS - Windows 7, 8, 10 and 11; Wired USB connection via USB 2.0; Package includes 1split keyboard, 1 vertical mouse, manual

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