Best Ergonomic Mice for People with Tremors

With so many choices out there, picking the right takes time.

Some models looked good on paper, but only a few delivered in real use.

One stood out across the board.

1
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
9.9
Amazon.com
2
ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for Windows, Mac OS, Black
ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for...
9.3
Amazon.com
3
Ergonomic Mouse, LEKVEY Vertical Wireless Mouse - Rechargeable 2.4G Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, Mac, PC, Computer, Desktop, Notebook etc, Black
Ergonomic Mouse, LEKVEY Vertical Wireless Mouse - Rechargeable 2.4G Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, Mac,...
8.9
Amazon.com
4
Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
8.7
Amazon.com
5
PHILIPS Ergonomic Mouse - Vertical Mouse with 800/1200/1600 Adjustable DPI, 6 Silent Buttons Design for S/M Hands, Auto Power Saving,Light Weight, 2.4GHz Wireless Mouse for Laptop, Desktop, PC-Black
PHILIPS Ergonomic Mouse - Vertical Mouse with 800/1200/1600 Adjustable DPI, 6 Silent Buttons Design for S/M Hands, Auto Power Saving,Light Weight, 2.4GHz...
8.6
Amazon.com

Top Pick

This is the product that stood out most — for performance, price, and overall value.

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black

$29.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 26, 2025 4:50 am

Features

Part Number AK-98ANWVM-UBA
Model AK-98ANWVM-UBA
Color Black
Is Adult Product
  • Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
  • 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
  • Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.

Top Picks Compared

Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black

$29.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 26, 2025 4:50 am

Features

Part Number AK-98ANWVM-UBA
Model AK-98ANWVM-UBA
Color Black
Is Adult Product
  • Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
  • 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
  • Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.

ProtoArc Ergonomic Mouse, EM11 NL Bluetooth Rechargeable Wireless Vertical Mouse, 3 Multi-Device Connectivity for Computer/PC/Laptop, 2.4GHz Optical Mice for...

$26.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 26, 2025 4:50 am

Features

Part Number Protoarc B0CX18LHWS
Model EM11 NL
Warranty 2 YEAR
Color Black
Size One Size
  • Connect up to 3 Devices: This ergonomic wireless mouse features dual BT 5.0 and 2.4G USB connectivity modes for simultaneous connection of up to 3 different devices, and is compatible with Windows 8, Windows 10 or higher, Mac OS X 10.12 or higher, and Android 4.3 or higher
  • Rechargeable Ergonomic Mouse: The Bluetooth Vertical Mouse has a built-in 500mAh Li-Ion battery that can be conveniently recharged using the included Type-C cable
  • Ergonomic Vertical Design: The ergonomic mouse wireless keeps your wrist naturally straight, putting your forearm and wrist in a more natural and relaxed position, which can reduce discomfort and strain, helping to improve productivity and reduce the risk of repetitive strain injuries compared to a standard mouse. Warm tips: We encourage you to relax your palm and hold the mouse naturally when using a vertical mouse
  • Learning curve: Since it takes a learning curve to get used to the shape when using our ergonomic mouse for the first time, it may cause inconvenience to your mouse grip, We recommend that you take 1-2 weeks to get used to it, as many users find that it will help reduce the pressure and pain on your wrist caused by long-term use of the mouse and improve comfort
  • Notes: We recommend that small to medium hands use our ergonomic vertical mouse. Please measure the size before ordering for a better fit and more comfort
  • Adjustable Dpi & High Performance: 1000/1600/2400 DPI levels provide higher sensitivity than standard optical mice for precise optical tracking; with the back and forward buttons, you can easily navigate websites and increase work efficiency. Note: All buttons are not programmable and the forward and back buttons are not compatible with Mac OS systems
  • Quiet Clicking: The silent click sound of the left and right mouse buttons help you focus on your work, Note:the middle scroll wheel and and the back/forward buttons are not silent.

Ergonomic Mouse, LEKVEY Vertical Wireless Mouse - Rechargeable 2.4G Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, Mac,...

$24.99 $39.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 26, 2025 4:50 am

Features

Part Number 7L-01
Model 7L-01
Warranty 1
Color Black
Release Date 2018-08-01T00:00:01Z
  • Ergonomic, Sleek and Rechargeable Design: Scientific ergonomic design encourages healthy neutral " handshake " wrist and arm positions for smoother movement and less overall strain. ** Most customers find it significantly reduces wrist pain and becomes very comfortable after just a 3-5 day adjustment
  • Multifunction and Convenient: Advanced " Page Back " and " Page Forward " functionality buttons provide convenience when web page browsing. 3 DPI levels ( 800 /1200/1600 ) -- Easily adjusts the sensitivity of the mouse
  • High-Capacity Rechargeable Battery: Built-in rechargeable battery. You no longer need to buy batteries, enjoy over 150 hours of continuous use on a single charge, very convenient !! Easy To Use -- One nano USB receiver at the bottom of the mouse, Just Plug and Play! No Bluetooth pairing or drivers needed
  • Widely Compatible: Widely compatible with Windows 2000 / XP / Vista / 7 / 8 / 10 / Linux. This Lekvey ergonomic mouse is also compatible with Mac OS. Once you get used to the vertical mouse, you'll love it so much and never want to go back to a regular one!
  • Lekvey Wireless Ergonomic Mouse: Revolutionize your work experience! Are you tired of using traditional mice that strain your wrist? Say goodbye to discomfort and hello to the Lekvey wireless carpal tunnel mouse! Designed with your ergonomic needs in mind, this innovative vertical ergonomic mouse offers a whole different level of comfort and efficiency
  • Package Includes: 1× Lekvey Rechargeable Wireless Vertical Ergonomic Mouse ( Size: 5.0" x 3.0" x 2.5"; recommended for medium or large hands), 1× 2.4G USB Receiver (in the bottom of the mouse), 1× 150cm Type-C Charging Cable, 1× User Manual. Backed by an industry-leading 36-month manufacturer's warranty

Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100

$25.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 26, 2025 4:50 am

Features

Part Number AK-98ANWVM-BA-0013
Model AK-98ANWVM-BA
Color Black
  • Ultimate Comfort: Embrace the comfort of Anker's Ergonomic Mouse, scientifically designed to encourage healthy neutral "handshake" wrist and arm positions. This wired mouse ensures smoother movement and significantly less strain, making it an ideal choice for extended computer use.
  • Enhanced Sensitivity: Experience precision like never before with our 1000/1600 DPI Resolution Optical Tracking Technology. This wired ergonomic mouse offers superior sensitivity compared to standard optical mice, ensuring smooth and precise tracking on a variety of surfaces to boost your productivity and computing experience.
  • Effortless Navigation: Navigate webpages with ease using the added next/previous buttons. This ergonomic wired mouse is not only ideal for internet surfers but also for gamers and professionals who spend long hours on the computer.
  • Compact and Lightweight: The Anker Vertical Ergonomic Optical Mouse, with its 1.5m/4.9ft USB cable and dimensions of 120*62.8*74.8 mm, offers a lightweight design of just 5.3 oz, ensuring a comfortable and convenient user experience.
  • Customer Value: Our package includes 1 Anker Vertical Ergonomic Optical Wired Mouse (with 4.9 ft cable), and a detailed instruction manual. We are committed to our customers and offer an 18-month warranty along with a lifetime technical support guarantee.

PHILIPS Ergonomic Mouse - Vertical Mouse with 800/1200/1600 Adjustable DPI, 6 Silent Buttons Design for S/M Hands, Auto Power Saving,Light Weight, 2.4GHz...

$26.99 $29.99
PRIMEPRIME
in stock
Amazon.com
Amazon price updated: September 26, 2025 4:50 am

Features

Part Number SPK
Model SPK
Warranty 1 year warranty
Color Black
Release Date 2025-07-05T00:00:01Z
Size Small/Medium
  • Vertical design,reduce wrist fatigue - Say goodbye to the traditional mouse's “slumped” position! This 57° ergonomic vertical mouse naturally fits the palm like a hand grip, allowing the arm and wrist to maintain a relaxed state, long time office, game is not sore and not tired
  • Optimized for Small to Medium Hands - The wireless mouse for laptop has 6 Silent Button keys layout (forward/backward /DPI) switch fit medium and small hand, comfortable grip without fatigue
  • 2.4G wireless speed response, one-key switch DPI - Stable as wired, free without delay! The wireless mouse has 2.4G technology with 3 DPI adjustment (800/1200/1600), whether it's efficient office or intense game, only click, the speed of switching at will
  • Noise canceling - Left click? Right click? All “silent mode”! With no noise mice, you can say goodbye to the “mouse symphony” when working late at night or presenting at a meeting
  • Intelligent hibernation & lightweight mice- Intelligent sleep mode automatically sleeps when idle. Lightweight and compact mouse, easy to stuff into your bag, convenient for traveling and working
  • Note: The product includes batteries wrapped in plastic film—remove before use

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Digital Wellness Labs
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