Top 5 Best Lightweight Ergonomic Mice
Not every is worth considering in 2025.
We looked at reviews, specs, and overall performance to narrow it down.
One stood out across the board.
1
Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
9.6
Amazon.com
2
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
9.6
Amazon.com
3
TECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 12 Months...
9.2
Amazon.com
4
Vassink Ergonomic Mouse, Rechargeable Wireless Mouse, 2.4GHz Rechargeable Wireless Vertical Optical Mice with USB Receiver, 6 Buttons for Laptop, PC,...
9.1
Amazon.com
5
Wireless Mouse Ergonomic Vertical Pink Rechargeable Silent Upright Comfortable Carpal Tunnel Ergo Optical Cordless Mice for Small Middle Hands for PC Laptop...
8.4
Amazon.com
Top Pick
This is the product that stood out most — for performance, price, and overall value.
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | AK-98ANWVM-UBA |
| Model | AK-98ANWVM-UBA |
| Color | Black |
| Is Adult Product |
- Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
- 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
- Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
- Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
- Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.
Other Options That Stood Out
Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse for Work, Multi-Device Connectivity, 800/1200 /1600 DPI, 5 Buttons for Laptop, Desktop, PC, MacBook - Black
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | AK-98ANWVM-UBA |
| Model | AK-98ANWVM-UBA |
| Color | Black |
| Is Adult Product |
- Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
- 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
- Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
- Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
- Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.
Anker Ergonomic Optical USB Wired Vertical Mouse 1000/1600 DPI, 5 Buttons CE100
$25.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | AK-98ANWVM-BA-0013 |
| Model | AK-98ANWVM-BA |
| Color | Black |
- Ultimate Comfort: Embrace the comfort of Anker's Ergonomic Mouse, scientifically designed to encourage healthy neutral "handshake" wrist and arm positions. This wired mouse ensures smoother movement and significantly less strain, making it an ideal choice for extended computer use.
- Enhanced Sensitivity: Experience precision like never before with our 1000/1600 DPI Resolution Optical Tracking Technology. This wired ergonomic mouse offers superior sensitivity compared to standard optical mice, ensuring smooth and precise tracking on a variety of surfaces to boost your productivity and computing experience.
- Effortless Navigation: Navigate webpages with ease using the added next/previous buttons. This ergonomic wired mouse is not only ideal for internet surfers but also for gamers and professionals who spend long hours on the computer.
- Compact and Lightweight: The Anker Vertical Ergonomic Optical Mouse, with its 1.5m/4.9ft USB cable and dimensions of 120*62.8*74.8 mm, offers a lightweight design of just 5.3 oz, ensuring a comfortable and convenient user experience.
- Customer Value: Our package includes 1 Anker Vertical Ergonomic Optical Wired Mouse (with 4.9 ft cable), and a detailed instruction manual. We are committed to our customers and offer an 18-month warranty along with a lifetime technical support guarantee.
TECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 12 Months...
$26.99
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | TK-MS007 |
| Model | TK-MS007 |
| Warranty | 3 years |
| Color | Black |
- 【Seamless Switching Between Three Devices】The ergonomic mouse features Bluetooth (5.0/3.0) and 2.4GHz USB A modes for connectivity. When connected via Bluetooth, The vertical mouse can effectively reduces the usage of your USB-A port (Bluetooth mode can connect to two devices simultaneously), In 2.4GHz connection mode, simply plug in the USB receiver for a quick connection. Press and hold the bottom button of the mouse for 3 seconds to enter the connection and pairing state. Short press the button to switch connection modes and improve work efficiency.(Note: The 2.4GHz receiver is built into the bottom of the mouse).
- 【Higher DPI & 6 Adjustable Levels】This vertical ergonomic mouse is equipped with a high-performance chip and features 6 adjustable DPI levels (4800/3200/2400/1600/1200/800) to meet your daily needs. wireless mouse upgraded technology allows this ergonomic mouse to operate smoothly on different types of surfaces. When changing the DPI, the light will flash, with the number of flashes corresponding to the DPI level.
- 【Silent Mouse】This computer mouse operates quietly, allowing for usage even in quiet environments like libraries. Additionally, the vertical mouse provides nearly silent clicks, helping avoid disturbances to others and ensuring your work or study remains undisturbed (Note: Only the left and right click buttons of the mouse are silent; other function buttons are not silent).
- 【Ergonomic Design】The wireless mouse's ergonomic design offers ultimate comfort by placing your palm at a near-vertical angle on the desktop, reducing pressure and pain on your wrist caused by prolonged inverted mouse usage (Note: Mouse is designed for right-handed use only).
- 【Broad Compatibility and Low Battery Warning】The wireless computer mouse is compatible with various devices, including Windows, Mac, Chrome, and Linux laptops (side buttons are not compatible with macOS). Additionally, this bluetooth mouse for laptops automatically enters deep sleep mode after approximately 10-30 minutes of inactivity to conserve power; you can awake it by pressing the right or left button. Note: We recommend using branded batteries to ensure the mouse's longevity. When the battery is low, the LED light will blink (Requires 2 AAA batteries, not included).
- 【36 MONTHS WARRANTY】If you encounter any problems in using the product, please feel free to contact our professional customer service team, enjoying TECKNET 36 Months Warranty (Registered Only).
Vassink Ergonomic Mouse, Rechargeable Wireless Mouse, 2.4GHz Rechargeable Wireless Vertical Optical Mice with USB Receiver, 6 Buttons for Laptop, PC,...
$14.99
$18.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | VAS9 |
| Model | 9399d2f1-9940-487f-94d0-80d78f8b6bb0 |
| Warranty | It is better to use it after receiving the mouse fully charged |
| Color | Black |
- ☛【Ergonomics-Wireless Mouse】The vertical wireless ergonomic mouse is designed to fit the size and contour of the palm, reducing the pressure on the palm and making your control of the wireless mice more comfortable and natural.
- ★【Efficient and Sensitive-Easy to Use】The ergonomic mouse has 6 convenient buttons design, plug and play; Adjustable mouse movement speed. Optical tracking technology has higher sensitivity than standard optical mouse, usable Smooth and precise tracking on a variety of surfaces.
- ☛【Quiet Design-Fashionable Charging】The wireless mouse adopts a button mute design, which is more suitable for public places such as libraries, dormitories, offices, high-speed rail planes, etc.; with built-in lithium battery and USB data cable charging device, making your use more fashionable Convenient.
- ★★★【Long Life-More Durable】The high-quality optical wireless mouse has been tested for over 5 million mouse clicks. The rechargeable feature makes this wireless mouse more durable.(It is better to use it after receiving the mouse fully charged)
- ☛【Strong Compatibility-Vassink Service】Support Windows 2000/ ME/ XP/ 7/ 8/ 10/ Vista/98, Mac OS, Linux, etc. Suitable for notebooks, PCs, laptops, computers, Macbooks and other equipment. We provide 12 months of worry-free after-sales service. If you encounter any problems with the wireless mouse during use, please feel free to contact us.
Wireless Mouse Ergonomic Vertical Pink Rechargeable Silent Upright Comfortable Carpal Tunnel Ergo Optical Cordless Mice for Small Middle Hands for PC Laptop...
$16.79
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | wireless mouse ergonomic |
| Model | wireless mouse ergonomic |
| Warranty | one year warranty |
| Color | Pink |
- Ergonomic Design for Small to Middle Hands: Our wireless vertical mouse is meticulously designed to fit comfortably in small to middle hands, promoting a natural grip and reducing strain, making it perfect for individuals with petite hands
- Silent and Quiet Operation: Enjoy a peaceful work environment with our carpal tunnel mouse's silent click technology, ensuring minimal noise and distractions, allowing you to focus on your tasks without interruptions
- Wireless and Cordless Convenience: Say goodbye to tangled cords and enjoy the freedom of wireless connectivity. Our rechargeable wireless mouse ergonomic right hand provides a clutter-free workspace and effortless mobility
- Rechargeable for Longer Usage: The wireless ergonomic mouse for carpal tunnel is equipped with a built-in rechargeable battery, eliminating the need for frequent battery replacements and ensuring uninterrupted usage
- Adjustable DPI for Precision: Choose from three adjustable DPI settings (800/1200/1600) to customize cursor speed of ergonomic wireless mouse ergonomic computer mouse rechargeable ergonomic mouse, providing precise control and smooth navigation across different applications
- Comfortable and Carpal Tunnel Friendly: The ergonomic vertical design of pink ergonomic mouse ergonomic vertical mouse promotes a neutral wrist position, helping alleviate wrist pain, carpal tunnel syndrome, and discomfort caused by prolonged computer useWide Compatibility: Compatible with MacBook, laptop, PC, Mac, and suitable for various operating systems, our vertical ergonomic mouse for small hands seamlessly integrates into your existing setup for hassle-free use
- Plug-and-Play Convenience: Simply plug in the USB receiver to your device, and our upright mouse for carpal tunnel wireless right hand is ready to use. No additional drivers or software installation required, ensuring a quick and easy setup
- Durable and Reliable: Crafted with premium materials, our ergonomic pc mouse for wrist pain computer mouse for carpal tunnel arthritic hands is built to withstand daily use, providing reliability and longevity for your work needs
- 【PERFECT GIFT】This pink ergonomic mouse is a perfect christmas gift for men women mom dad daughter wife boyfriend grandparents grandma grandpa teenage boy girl sister teacher brother coworker neighbor husband.Perfect Gift : This cute wireless mouse is a Perfect christmas gift or other festival gift for men women mom dad daughter wife boyfriend grandparents grandma grandpa teenage boy girl sister teacher brother coworker neighbor husband.Perfect Mothers Day Gift for Mother. Perfect Fathers Day Gift for Father
This post contains affiliate links. Purchases may earn me a commission at no extra cost to you.
