Top 5 Best Ergonomic Mice with Adjustable DPI
With so many choices out there, picking the right takes time.
Some models looked good on paper, but only a few delivered in real use.
The best option wasn’t the most expensive — but it delivered where it counts.
1
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
9.7
Amazon.com
2
TECKNET Ergonomic Wireless Mouse, Rechargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB Vertical Mouse Wireless for Laptop, 5...
9.2
Amazon.com
3
TECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 12 Months...
9
Amazon.com
4
E-YOOSO Ergonomic Mouse, Wireless Vertical Mouse with 6 Buttons, 5 Adjustable DPI Levels, Up to 4800 DPI, 2.4G and Bluetooth, Wired Optical Vertical Mice for...
8.7
Amazon.com
5
TECKNET USB Wired Mouse, 6-Button Corded Computer Mouse with 4 Adjustable DPI, Optical Computer Mice with Ergonomic Design and 5FT Cord for Laptop,...
8.4
Amazon.com
Top Pick
This is the product that stood out most — for performance, price, and overall value.
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
$19.99
PRIMEPRIME
in stock
Amazon.com
Features
| Warranty | 18 Months |
| Color | Black |
- 【Ergonomic Design】Ergonomic mouse with Ergonomic Design, 52°angle to the tabletop. A natural handshake position effectively relieves pressure on the wrist and arm, preventing RSI syndrome caused by long-term mouse use. It is the ideal choice for prolonged office work
- 【4800 High DPI】5 adjustable DPI settings: 4800/3200/2400/1600/800, catering to different usage habits. Even if you're new to it, you can easily master the mouse. TECKNET ergonomic wireless mouse optical tracking provides the smoothest and most precise cursor control on most surfaces
- 【Comfortable Shape for Small/Medium Hands】The shape is rounded and comfortable with no sharp corners. Unlike other mice, this mouse is more suitable for small/medium hands, bringing a comfortable using experience and slowing down wrist fatigue. Product size: 4.13in*2.55in
- 【Quick Click Buttons】The vertical mouse wireless added forward/back buttons provide convenience for web browsing. (Side buttons not supported on MAC OS).The features a silent click design, reducing click noise by over 99%, while ensuring optimal performance. This means you can feel every click but hardly hear any sound (note: forward/back buttons are not silent)
- 【Stable Wireless Connection】The ergonomic mouse wireless uses 2.4GHz wireless technology, providing a stable and accurate connection without the need for any drivers. Simply plug the USB receiver into your laptop to start using the mouse, with a connection range of up to 32ft
- 【Wide Compatibility】The mouse ergonomic is compatible with a wide range of devices and can be used on desktops, laptops, PCs, MacBooks and other devices. Works with Windows 11/10/8/7/XP and Mac OS X10.4. It has a silent feature that allows it to be used in libraries, homes, offices, and other situations where low sound levels are required
More Worth Considering
Here are the other options we recommend. Each brings something different to the table, depending on what you’re looking for.
TECKNET Ergonomic Mouse, 4800 DPI 5 Adjustable DPI Levels, Wireless Vertical Mouse, 6 Buttons, 2.4G Silent Mouse for Laptop, PC, Chromebook, Mac - Black
$19.99
PRIMEPRIME
in stock
Amazon.com
Features
| Warranty | 18 Months |
| Color | Black |
- 【Ergonomic Design】Ergonomic mouse with Ergonomic Design, 52°angle to the tabletop. A natural handshake position effectively relieves pressure on the wrist and arm, preventing RSI syndrome caused by long-term mouse use. It is the ideal choice for prolonged office work
- 【4800 High DPI】5 adjustable DPI settings: 4800/3200/2400/1600/800, catering to different usage habits. Even if you're new to it, you can easily master the mouse. TECKNET ergonomic wireless mouse optical tracking provides the smoothest and most precise cursor control on most surfaces
- 【Comfortable Shape for Small/Medium Hands】The shape is rounded and comfortable with no sharp corners. Unlike other mice, this mouse is more suitable for small/medium hands, bringing a comfortable using experience and slowing down wrist fatigue. Product size: 4.13in*2.55in
- 【Quick Click Buttons】The vertical mouse wireless added forward/back buttons provide convenience for web browsing. (Side buttons not supported on MAC OS).The features a silent click design, reducing click noise by over 99%, while ensuring optimal performance. This means you can feel every click but hardly hear any sound (note: forward/back buttons are not silent)
- 【Stable Wireless Connection】The ergonomic mouse wireless uses 2.4GHz wireless technology, providing a stable and accurate connection without the need for any drivers. Simply plug the USB receiver into your laptop to start using the mouse, with a connection range of up to 32ft
- 【Wide Compatibility】The mouse ergonomic is compatible with a wide range of devices and can be used on desktops, laptops, PCs, MacBooks and other devices. Works with Windows 11/10/8/7/XP and Mac OS X10.4. It has a silent feature that allows it to be used in libraries, homes, offices, and other situations where low sound levels are required
TECKNET Ergonomic Wireless Mouse, Rechargeable Mouse Wireless Silent for Carpal Tunnel Right Hand, 2.4GHz USB Vertical Mouse Wireless for Laptop, 5...
$26.99
PRIMEPRIME
in stock
Amazon.com
Features
| Model | TK-MS007 |
| Warranty | 36 Months |
| Color | Grey |
- Ergonomic Design: TECKNET ergonomic wireless mouse compared to traditional mice, the vertical design allows the wrist and arm to be naturally relaxed, reducing hand fatigue and discomfort caused by long-term use of the mouse. The ergonomic wireless mouse enables the hand to maintain a more natural posture, helps reduce pressure on the shoulder and neck, and prevents or alleviates hand problems caused by sitting for a long time. Making it the perfect ergonomic wireless mouse for daily tasks.
- Rechargeable Convenience: The rechargeable mouse wireless has a built-in 600mAh rechargeable battery, which can be fully charged in just 1.5 hours. The rechargeable mouse wireless can be used continuously for 2 months (the actual time depends on habits and frequency) when fully charged. It is charged via the Type-C interface and comes with a charging cable. Tips: It enters power saving mode (complete shutdown) after 8 minutes of inactivity - press the right or left button to wake it up.
- Stable Wireless Connection: The ergonomic wireless mouse adopts advanced 2.4 GHz wireless technology, ensuring stable and quick performance within a 10m distance without interference. This vertical mouse wireless supports plug-and-play, so connect the included USB receiver to the USB port of your computer, no additional driver is needed.
- Silent Operation: This ergonomic wireless mouse uses silent-click technology to minimize noise in shared spaces. Vertical mouse wireless allows you to work anywhere, such as Cafe, libraries, hospitals, bedrooms with sleeping babies, etc., improving your work efficiency without worrying about disturbing others, allowing you to enjoy a quiet working environment. This silent ergonomic wireless mouse is perfect for working on the go.
- Adjustable DPI: Vertical Mouse Wireless with 5 adjustable DPI settings, 4800/3200/2400/1600/800. Compared with traditional optical mice, this differentiated optical tracking technology provides higher sensitivity, and the advanced TeckNet Tru-Wave optical tracking technology ensures accurate tracking on most surfaces (except glass). Multiple DPI levels allow you to choose different DPIs in different office situations, or choose the DPI that suits you best according to your usage habits.
- Wide Compatibility: TECKNET USB-A ergonomic wireless mouse is crafted for carpal tunnel support. This vertical mouse wireless employs 2.4GHz technology, ensuring compatibility with numerous devices like desktops, laptops, and PCs. The vertical mouse wireless seamlessly fits most computer models featuring a USB-A port, except those equipped with USB-C interfaces.
TECKNET Ergonomic Mouse, Wireless Bluetooth Vertical Mouse, 4800 DPI Optical Tracking, 6 Adjustable DPI, Quiet Clicks, 2.4GHz with USB A Receiver, 12 Months...
$26.99
$29.99
PRIMEPRIME
in stock
Amazon.com
Features
| Part Number | TK-MS007 |
| Model | TK-MS007 |
| Warranty | 3 years |
| Color | Black |
- 【Seamless Switching Between Three Devices】The ergonomic mouse features Bluetooth (5.0/3.0) and 2.4GHz USB A modes for connectivity. When connected via Bluetooth, The vertical mouse can effectively reduces the usage of your USB-A port (Bluetooth mode can connect to two devices simultaneously), In 2.4GHz connection mode, simply plug in the USB receiver for a quick connection. Press and hold the bottom button of the mouse for 3 seconds to enter the connection and pairing state. Short press the button to switch connection modes and improve work efficiency.(Note: The 2.4GHz receiver is built into the bottom of the mouse).
- 【Higher DPI & 6 Adjustable Levels】This vertical ergonomic mouse is equipped with a high-performance chip and features 6 adjustable DPI levels (4800/3200/2400/1600/1200/800) to meet your daily needs. wireless mouse upgraded technology allows this ergonomic mouse to operate smoothly on different types of surfaces. When changing the DPI, the light will flash, with the number of flashes corresponding to the DPI level.
- 【Silent Mouse】This computer mouse operates quietly, allowing for usage even in quiet environments like libraries. Additionally, the vertical mouse provides nearly silent clicks, helping avoid disturbances to others and ensuring your work or study remains undisturbed (Note: Only the left and right click buttons of the mouse are silent; other function buttons are not silent).
- 【Ergonomic Design】The wireless mouse's ergonomic design offers ultimate comfort by placing your palm at a near-vertical angle on the desktop, reducing pressure and pain on your wrist caused by prolonged inverted mouse usage (Note: Mouse is designed for right-handed use only).
- 【Broad Compatibility and Low Battery Warning】The wireless computer mouse is compatible with various devices, including Windows, Mac, Chrome, and Linux laptops (side buttons are not compatible with macOS). Additionally, this bluetooth mouse for laptops automatically enters deep sleep mode after approximately 10-30 minutes of inactivity to conserve power; you can awake it by pressing the right or left button. Note: We recommend using branded batteries to ensure the mouse's longevity. When the battery is low, the LED light will blink (Requires 2 AAA batteries, not included).
- 【36 MONTHS WARRANTY】If you encounter any problems in using the product, please feel free to contact our professional customer service team, enjoying TECKNET 36 Months Warranty (Registered Only).
E-YOOSO Ergonomic Mouse, Wireless Vertical Mouse with 6 Buttons, 5 Adjustable DPI Levels, Up to 4800 DPI, 2.4G and Bluetooth, Wired Optical Vertical Mice for...
$16.99
$18.99
PRIMEPRIME
in stock
Amazon.com
Features
| Model | X-45 |
| Warranty | 12 Months Warranty |
| Color | Red Black |
- 【ERGONOMIC VERTICAL MOUSE】:The ergonomic wireless vertical mouse is meticulously crafted with a unique vertical shape fits the natural curve of your hand, which minimizes wrist strain, and efficiently reduces wrist discomfort from prolonged usage. This makes using the ergonomic wireless mouse more natural and pleasant
- 【VERSATILE CONNECTIVITY & COMPATIBILITY】:Plug and Play. This vertical wireless mouse has 3 in 1 connection modes, featuring both 2.4G wireless and Bluetooth, wired connectivity options, empowering with unparalleled flexibility in diverse technological environments. You can control two devices at the same time, switch freely between Android, tablet and Mac with just one button
- 【MULTIFUNCTION AND CONVENIENT】:Advanced "Page Back" and "Page Forward" functionality buttons provide convenience when web page browsing. This ergonomic mouse with 5 adjustable DPI levels(800 /1200/1600/2000/4800) -- Users can adjust responsiveness depending on their need and/or preference. Easily adjusts the sensitivity of the optical vertical mouse
- 【WIDELY USED】:The 3 in 1 wired, wireless and bluetooth vertical wireless mouse is suitable for use in the office, home, school. Lightness and easy to carry, you can put it in the computer bag and take it to the coffee shop, library, office and business trip
- 【WIDE COMPATIBILITY】:Highlight the sleek and professional design of the mouse, making it suitable for corporate and home office settings. The wireless vertical mouse is compatible with a wide range of devices. It fits desktops, laptops, PCs, MacBooks, and other devices, making it almost universally suitable for most computer devices on the market
- 【NOTE】:The size of this vertical mouse is a little bit bigger than the normal office computer mouse, but it is not completely a large-sized mouse. Please choose carefully before buying
TECKNET USB Wired Mouse, 6-Button Corded Computer Mouse with 4 Adjustable DPI, Optical Computer Mice with Ergonomic Design and 5FT Cord for Laptop,...
$9.99
PRIMEPRIME
in stock
Amazon.com
Features
| Model | 013-L |
| Warranty | 36 Months |
| Color | Blue |
- 【High Precision and Durability】: TECKNET Tru-Wave technology wired computer mouse provides precise, intelligent cursor control and tracking on many surface types, even on smooth surfaces with glass. Tested for over 6 million keystrokes, the wired mouse ensures responsive clicks and a longer lifespan for daily use.
- 【4 Adjustable DPI and 6 Buttons】: 4-level DPI settings (1000/1600/3200/6400) to meet your needs both in home and office. 6 buttons enable superior productivity and efficiency to meet all your computer needs. Moving quickly between documents or browsing your favorite Web sites is a breeze with large, easy-to-reach Back/Forward buttons.
- 【Ergonomic Design】: The shaped design and soft rubber grips conform to the hand and are designed to be comfortable to hold. The compact size enables it to be able to be taken wherever desired for use on the computer whether at home, at work or anywhere else.
- 【Plug and Play】: Simply plug in the USB cable to power your mouse, eliminates the trouble of replacing batteries. No software or downloads required. The 5FT of USB cable is the perfect length for a USB wired mouse and adapts to almost any computer setup with no lag.
- 【Wide Compatibility】：Compatible with Windows 2000,2003, XP, VISTA, 7, 8, 10, 11 and Chromebook, Mac (side buttons not work on Mac)
- 【36 MONTHS SUPPORT】: If you encounter any problems in using the product, please feel free to contact our professional customer service team, enjoying TECKNET 36 Months Warranty (Registered Only)
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